Are Surgical Trials with Negative Results Being Interpreted Correctly?

HBV Subgenotypes D1, D2, D-del! Are ‘Old‘ Genotyping Methods Interpreted Correctly?

Implication for health policy/practice/research/medical education: Molecular virology methods are developing rapidly and allow new insights into molecular epidemiology of viral infections. Despite the recent introduction of advanced methodology to genotype hepatitis B virus, using old but rapid and inexpensive genotyping tools like restriction fragment length poly-morphism have been utilized wi...

hbv subgenotypes d1, d2, d-del! are ‘old‘ genotyping methods interpreted correctly?

Are laboratories reporting serum quantitative hCG results correctly?

BACKGROUND Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone that exists in multiple forms. Immunoassays commonly used in clinical laboratories measure intact hCG, total beta hCG (intact hCG + hCG free beta-subunit), and/or hCG free beta-subunit. Measurement of serum concentrations of hCG is useful for confirmation and monitoring of pregnancy, diagnosis of trophoblastic...

Is the airway volume being correctly analyzed?

INTRODUCTION The aim of the study was to determine the most accurate threshold value for airway volume quantification based on specific experimental conditions. METHODS Ten scans from the airway prototype were obtained by using cone-beam computed tomography. The volume from each scan was measured with 8 values (25, 50, 70, 71, 72, 73, 74, and 75) of the threshold tool from the Dolphin softwar...

Negative results of randomized clinical trials published in the surgical literature: equivalency or error?

HYPOTHESIS We hypothesized that review of randomized controlled clinical trials (RCTs) with nonstatistically significant or "negative" results published in the surgical literature do not have appropriate statistical power to demonstrate equivalency between treatment arms. DATA SOURCES AND STUDY SELECTION The MEDLINE database was searched to obtain reports of all RCTs with negative results pub...